Circular Dichroism Microspectroscopy
Circular Dichroism (CD) microspectroscopy and imaging.
Introduction
CRAIC Technologies™ is proud to offer Circular Dichroism microspectroscopy. This capability is important in biology and materials science as Circular Dichroism (CD) is the most widely used chiroptical method for analyzing chiral substances and characterizing biomolecules. By incorporating it into a microspectrometer, one is now able to acquire CD microspectra of micron-scale samples.
Designed for many different applications, the CD microspectroscopy package is exclusive to CRAIC Technologies microspectrometers. Contact us today to learn more about the novel technology.
Circular Dichroism Microspectroscopy
Spectroscopy of Chiral Substances
| CD microspectroscopy is a valuable method for studying metal-protein interactions and resolving individual d–d electronic transitions. Additionally, it has proven to be highly effective for determining enantiomeric excess in asymmetric synthesis as well as the optical properties of nanostructured arrays. |  |
Science of Circular Dichroism
Circular Dichroism (CD) spectroscopy is a technique that measures the differential absorption of left- and right-circularly polarized light by chiral molecules. This phenomenon arises due to the molecular asymmetry in chiral compounds, such as proteins, DNA, and other biomolecules. CD microspectroscopy integrates the capabilities of CD spectroscopy with that of an optical microscope.
CD microspectroscopy provides information about the secondary and tertiary structures of biomolecules, their folding, stability, and interactions with ligands or metals. It is widely used to analyze conformational changes, study enantiomeric purity, and characterize structural features in asymmetric synthesis. This non-destructive technique is particularly valuable in biochemistry, structural biology, and pharmaceutical research for its sensitivity and versatility in studying chirality and molecular structure.
Applications
Applications
- Nanostructured Arrays
- Protein and Biomolecule Analysis
- Chiral Substance Analysis
- Ligand-Binding Studies
- Conformational Studies
- Pharmaceutical Applications
- ...and much more.
Support
CRAIC Technologies provides service and support for it's instruments worldwide. CRAIC Technologies service engineers offer instrument repair, maintenance, training and technical support for all aspects of CRAIC Technologies products.
Perfect Vision for Science™
The lit microscope base and the lit octagonal optical head are trademarks of CRAIC Technologies, Inc. CRAIC Technologies, 2030PV™, FLEX™, 508PV™, Apollo™, GeoImage™, rIQ™, Lambdafire™, Lightblades™ and "Perfect Vision for Science" are all trademarks of CRAIC Technologies, Inc. Instrument features offered depend upon instrument configuration. Features listed here may not be present in some configurations.
*Features and specifications depend upon instrument configuration. Specifications subject to change without notice.
UV-visible-NIR microscopes, UV-visible-NIR microspectrometers and Raman microspectrometers are general purpose laboratory instruments. They have not been cleared or approved by the European IVD Directive, the United States Food and Drug Administration or any other agency for diagnostic, clinical or other medical uses.
